Hydroxychloroquine Side Effects in Children
Hydroxychloroquine Side Effects (also known as chloroquine) is an anti-maladminister. It works by inhibiting the formation of malarial cells in the blood. Malaria is a disease caused by parasites that live in the body, and these parasites must be destroyed in order to cure the illness. In many cases, doctors use these drugs to treat serious malaria infections. However, some people have had problems with hydroxychloroquine, and they have developed serious side effects after taking the medicines.
Most of the hydroxychloroquine side effects are linked to hair loss. Hair loss is most often a side effect of other types of drugs, and it can interfere with your ability to see properly or perform other physical tasks. Because this drug is used to treat malaria, it can sometimes cause severe hair loss. If you experience excessive hair loss, you should talk to your doctor about a possible treatment for the condition.
Other common side effects of hydroxychloroquine are changes in heart rhythm, palpitations, and increased blood pressure. Your heart rhythm can become slightly irregular when you take the medication, and you may experience shortness of breath after taking a dose. If you experience palpitations, however, this can also be an indication that you are having an allergic reaction. Because of this possibility, you should let your doctor know about all symptoms that you experience so that you can determine whether your reactions are caused by the medication or something else. If your heart rhythm changes while you are taking the medication, you should contact your doctor right away.
One of the most dangerous side effects of hydroxychloroquine occurs when it is combined with other medications. This medication is commonly taken with other antifungal medications such as erythromycin, troches (antitheliocyes), and other antibiotics. When taken together, hydroxychloroquine can result in severe muscle weakness. Hydroxychloroquine and erythromycin have been known to cause seizures in certain individuals who are taking a large amount of these medications. Individuals with a history of heart problems or liver problems are especially at high risk for complications when hydroxychloroquine is combined with other medicines.
Another severe side effect of hydroxychloroquine occurs when it is taken in conjunction with malaria. Although there are no serious interactions between the two drugs, the combination can result in severe vomiting, nausea, and diarrhea. If you become dehydrated while taking hydroxychloroquine, you can suffer from potentially life-threatening electrolyte imbalances, which can cause seizures or even death. To prevent this from happening, talk to your doctor about your concerns about using this combination drug with malaria. The number of patients with either severe dehydration or malaria who were reported to be treated with hydroxychloroquine has increased since the drug was approved for use with malaria.
Hydroxychloroquine is not the only NSAID available for the treatment of arthritis. Several other drugs have similar activity in reducing the arthritis pain that is associated with several types of systemic Lupus erythematosus (SLE), including doesletosin (ddI, Discovigan), leupeptin (Lepistatin), and rusapir (Risperdal). Before deciding upon an NSAID for the treatment of your SLEs, it is important to discuss your symptoms with your doctor and obtain a complete medical history. Some patients who are receiving these other drugs but not hydroxychloroquine are experiencing serious adverse reactions to these other drugs. Therefore, you should also consider the possibility that hydroxychloroquine may lead to other serious conditions.
Because of the potential for serious adverse effects, the Food and Drug Administration (FDA) has evaluated the safety of hydroxychloroquine in terms of its possible interaction with other medications and other substances known to affect the function of the cardiovascular system, such as cholesterol and triglycerides. One of these substances is called quercetin, which is a component of red wine. These antigens are responsible for inhibiting the production of “bad” cholesterol in the body. However, quercetin has also been found to interact adversely with hydroxychloroquine in the development of cyclic AMP, an increase in intracellular calcium, and an increase in free radical activity at cellular levels. These potential interactions could result in the suppression of the benefits of hydroxychloroquine therapy for SLE patients. Further studies are currently being conducted to assess the effect of quercetin on hydroxychloroquine and to determine whether additional drug interactions may exist.
Because the cause of SLE is often unknown, the treatment of this condition is based on a case-by-case basis. In the majority of reported cases, hydroxychloroquine was administered on the basis of the clinical picture generated by the treating physician. The use of alternative therapies in the treatment of SLE has been extremely popular because alternative medicines have been found to be effective in the control of severe symptoms of SLE and other diseases, including sudden dizziness and pounding heartbeats. In view of the above-mentioned potentials for adverse hydroxychloroquine/quercetin interactions, and in view of the lack of evidence that supports the efficacy of quercetin in the treatment of SLE, alternative medicines are now being recommended in place of hydroxychloroquine. These alternative medicines include herbs, vitamins, mineral dietary supplements, and lifestyle modifications.